The presence of the central DNA flap in HIV vectors enhances gene transduction in primary neural cells. To determine whether TRIP vectors, which include the central DNA flap, allow improved ...
The present study was designed to characterize transduction of non-human primate brain and spinal cord with AAV5 viral vector after parenchymal delivery. AAV5-CAG-GFP (1 × 10 13 vector genomes per ...