Synaptic pruning is a crucial neurodevelopmental process through which the brain refines its neural circuitry by systematically eliminating excess or weak synaptic connections. During early childhood ...

Synaptic pruning is the process in which the brain removes neurons and synapses that it does not need. This usually takes place when a person is 2–10 years old. The brain contains millions of neurons ...

In the Alzheimer’s disease brain, synaptic loss correlates with cognitive decline, and is considered a sign of disease progression. But is synaptic loss always bad? Provocative new data from several ...