A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune ...

The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and ...

The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...

The translation of nanomaterials from fundamental research to clinical applications in biomedicine faces multifaceted challenges, including concerns regarding biocompatibility and long-term toxicity, ...

A large-scale international study, led by researchers from the Gray Faculty of Medical and Health Sciences at Tel Aviv ...

Over the past decade, the advent of immune checkpoint blockade (ICB) therapy has transformed cancer treatment. Unlike conventional cytotoxic and targeted therapies, immunotherapy leverages both the ...

A class of ultrasmall fluorescent core-shell silica nanoparticles developed at Cornell is showing an unexpected ability to rally the immune system against melanoma and dramatically improve the ...

More than 90% of cancer deaths in America are attributable to metastasis, when cancer spreads from its original site to other parts of the body. Researchers at the Johns Hopkins Kimmel Cancer Center ...

In recent years, cancer immunotherapy has transformed the treatment landscape for a wide range of malignancies, offering ...

Common diabetes drugs may do more than regulate blood sugar—they could also influence how cancers grow, spread, or slow down.