Gene therapy with voretigene neparvovec-rzyl partially restores geniculostriate pathway function in LCA2 patients, improving visual processing. Initial LCA2 pathology shifts visual processing from the ...

Vision is one of the most complex functions of our brain and requires a seamless interaction between many different brain structures to decode shapes, colours, depths, and movements and turn them into ...

For decades, restoring sight after severe eye damage sat firmly in the realm of science fiction. Now a wave of converging ...

Prior investigations of rabbit and mouse retina have reported robust directionally selective retinal circuits impinging on directionally-selective ganglion cells (DSGC), while investigations of NHP ...

Improved understanding of a neural pathway connecting light-sensitive cells in the retina with the cortical brain regions involved in mood and cognition has implications for the development of ...

In the retina, age-related macular degeneration (AMD) affects the complex of photoreceptors, retinal pigment epithelium (RPE), Bruch’s membrane (BM) and the choriocapillaris, the innermost layer of ...

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply ...