Meta-analysis demonstrates that treatment effect on total GFR slope strongly predicts clinical endpoints. Study findings presented at the European Renal Association 2023 congress in Milan, Italy, ...

Recently a new definition of surrogate endpoint, the "principal surrogate," was proposed based on causal associations between treatment effects on the biomarker and on the clinical endpoint. Despite ...

A randomized double-blind phase II study of the Seneca Valley virus (NTX-010) versus placebo for patients with extensive stage SCLC (ES-SCLC) who were stable or responding after at least four cycles ...

A meta-analysis spanning more than 100 cardiology RCTs over three decades in more than a million patients offers a stern rebuke to the notion that nonfatal MI can serve as a surrogate for mortality, ...

Proteomic analysis for detection of NSCLC: Results of ACOSOG Z4031. This is an ASCO Meeting Abstract from the 2011 ASCO Annual Meeting I. This abstract does not include a full text component.

Neoadjuvant therapy that resulted in pathologic complete response (pCR) reduced the risk of breast cancer recurrence by 80%, pooled data from a phase II clinical trial platform showed. The results ...

CARY, N.C., June 22, 2020 /PRNewswire/ -- Critical Path Institute (C-Path) announced Wednesday, June 17, that its Transplant Therapeutics Consortium (TTC), of which Veloxis Pharmaceuticals is a member ...

This milestone opens a path for FibroScan ® to ultimately replace liver biopsy for patient enrollment and treatment response assessment in MASH drug development WESTBOROUGH, Mass., Sept. 8, 2025 ...

This milestone opens a path for FibroScan® to ultimately replace liver biopsy for patient enrollment and treatment response assessment in MASH drug development This is the first time the FDA is ...