Reactive oxygen species from smooth muscle mitochondria initiate cold-induced constriction of cutaneous arteries, AJP - Heart and Circulatory Physiology | DeepDyve
deepdyve.com
Reactive oxygen species from smooth muscle mitochondria initiate cold-induced constriction of cutaneous arteries, AJP - Heart and Circulatory Physiology | DeepDyve
Cold constricts cutaneous blood vessels by selectively increasing the activity of smooth muscle α 2 -adrenoceptors (α 2 -ARs). In mouse tail arteries, α 2 -AR constriction is mediated by α 2A -ARs at 37°C, whereas the cold-induced augmentation in α 2 -AR activity is mediated entirely by α 2C -ARs. Cold causes translocation of α 2C -ARs ...
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